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Invisible endometriosis
The importance of the microbiota in endometriosis
In episode 6, Carole Minker explains why the intestinal microbiota plays a central role in endometriosis, how it influences estrogens and lesions, and how to take care of them in practice.
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Summary
🔊 This program is an information program by a trained professional. This is generic advice and is not a personalized diagnosis. In all cases, we recommend that you be followed by a gynecologist and/or a midwife for individualized follow-up.
What you will learn in this episode
In this episode, Carole Minker explains the link between intestinal microbiota and endometriosis. A lesser-known but fundamental link: the microbiota directly influences estrogen metabolism, the immune system, and even the receptivity of the endometrium. You will also understand why oral health is part of the equation, and what concrete actions can be taken to take care of this ecosystem on a daily basis.
The microbiota and estrogens
The intestinal microbiota is a set of microorganisms with which we live in symbiosis in our intestine. It hosts 70-80% of the cells of the immune system and plays a central role in the metabolism of estrogens.
Here's how it works: estrogens circulate in the body, pass through the liver, which prepares them for elimination, and then arrives in the intestine. Normally, they are evacuated.
But when the microbiota is out of balance, which is often the case in endometriosis, it removes the markers that directed these estrogens out and returns them back into the circulation. The result: an excess of estrogens that nourishes the lesions.
Rebalancing the microbiota therefore means acting both on hormonal balance and on the immune system.
💡 Key figures
70 to 80% of the body's immune cells are concentrated in the intestine. This is why the state of the microbiota has a direct impact on the body's ability to regulate inflammation, a central issue in endometriosis.
Source: Penser Santé, based on data from the lymphoid tissue associated with the intestine (GALT).
Dysbiosis and intestinal permeability
In endometriosis, dysbiosis, i.e. the imbalance of the microbiota, can be both a cause and a consequence of the disease. It is often associated with increased intestinal permeability, also called leaky gut or porous intestine. When the intestine allows poorly digested molecules or bacteria to pass through, it creates inflammation throughout the body. And endometriotic lesions love inflammation.
Gluten: neither universal culprit, nor out of cause
A recent observational study showed that for every dietary change tested individually, including gluten, alcohol, or refined sugars, about 50% of women saw an improvement in their symptoms, and 50% saw no change.
Gluten should therefore not be eliminated in principle, but tested individually over two to three months, following its symptoms.
The endometrial microbiota
Contrary to what was believed until recently, there is a microbiota in the endometrium itself, which plays a role in its receptivity and in the ability to host an embryo. There is also a microbiota in endometriotic lesions. Some of the bacteria in there may come... from the mouth. This highlights the importance of good oral hygiene in the overall management of endometriosis.
🔎 Useful definitions
Dysbiosis : imbalance in the intestinal microbiota, which can be both a cause and a consequence of endometriosis. It is often associated with increased intestinal permeability and chronic low-grade inflammation.
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Gut permeability : a condition in which the lining of the intestine allows poorly digested molecules or bacteria to pass into the bloodstream, causing an inflammatory reaction throughout the body.
🎯 Actions concrètes
- Adopt the rainbow plate by varying the colors of plants during the week: orange carrots, red cabbage, beets, corn, green vegetables
- Each color provides different polyphenols that nourish the good bacteria in the microbiota.
- Integrate fermented foods: Kefir, kombucha, kimchi, kimchi, sauerkraut, yogurt, skyr, sourdough bread.
- Start once or twice a week if it's not already a habit.
- Test to see what's right for your gut.
- Ensure an adequate intake of fiber and omega-3:
- Fibers nourish good bacteria.
- Omega-3 supports the intestinal mucosa and bacterial performance: a dedicated episode in this program will help you choose them well.
- Taking care of your oral health:
- Avoid cavities, gingivitis and periodontitis
- The oral microbiota directly influences the intestinal microbiota, and bacteria from the mouth can be found even in endometriotic lesions.
- Schedule a dental check-up if it has not been done for a long time.
- Reduce what disrupts the microbiota:
- Alcohol, tobacco, chronic stress and some repeated medications are among the main factors that unbalance this ecosystem.
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Summary
🔊 This program is an information program by a trained professional. This is generic advice and is not a personalized diagnosis. In all cases, we recommend that you be followed by a gynecologist and/or a midwife for individualized follow-up.
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⭐ La série Invisible endométriose est possible grâce à la participation de Norsan. L'épisode Bonus leur est dédié, et vous en apprendrez plus sur les Oméga 3 dans l'épisode 9. Norsan, entreprise spécialiste en production d'Oméga 3 depuis 2013 sont le plus grand distributeurs d'Oméga 3 en pharmacie car leur Oméga 3 naturels et de haute qualité font partie aujourd'hui des meilleurs Oméga 3 disponibles sur le marché.
What you will learn in this episode
In this episode, Carole Minker explains the link between intestinal microbiota and endometriosis. A lesser-known but fundamental link: the microbiota directly influences estrogen metabolism, the immune system, and even the receptivity of the endometrium. You will also understand why oral health is part of the equation, and what concrete actions can be taken to take care of this ecosystem on a daily basis.
The microbiota and estrogens
The intestinal microbiota is a set of microorganisms with which we live in symbiosis in our intestine. It hosts 70-80% of the cells of the immune system and plays a central role in the metabolism of estrogens.
Here's how it works: estrogens circulate in the body, pass through the liver, which prepares them for elimination, and then arrives in the intestine. Normally, they are evacuated.
But when the microbiota is out of balance, which is often the case in endometriosis, it removes the markers that directed these estrogens out and returns them back into the circulation. The result: an excess of estrogens that nourishes the lesions.
Rebalancing the microbiota therefore means acting both on hormonal balance and on the immune system.
💡 Key figures
70 to 80% of the body's immune cells are concentrated in the intestine. This is why the state of the microbiota has a direct impact on the body's ability to regulate inflammation, a central issue in endometriosis.
Source: Penser Santé, based on data from the lymphoid tissue associated with the intestine (GALT).
Dysbiosis and intestinal permeability
In endometriosis, dysbiosis, i.e. the imbalance of the microbiota, can be both a cause and a consequence of the disease. It is often associated with increased intestinal permeability, also called leaky gut or porous intestine. When the intestine allows poorly digested molecules or bacteria to pass through, it creates inflammation throughout the body. And endometriotic lesions love inflammation.
Gluten: neither universal culprit, nor out of cause
A recent observational study showed that for every dietary change tested individually, including gluten, alcohol, or refined sugars, about 50% of women saw an improvement in their symptoms, and 50% saw no change.
Gluten should therefore not be eliminated in principle, but tested individually over two to three months, following its symptoms.
The endometrial microbiota
Contrary to what was believed until recently, there is a microbiota in the endometrium itself, which plays a role in its receptivity and in the ability to host an embryo. There is also a microbiota in endometriotic lesions. Some of the bacteria in there may come... from the mouth. This highlights the importance of good oral hygiene in the overall management of endometriosis.
🎯 Concrete actions
- Adopt the rainbow plate by varying the colors of plants during the week: orange carrots, red cabbage, beets, corn, green vegetables
- Each color provides different polyphenols that nourish the good bacteria in the microbiota.
- Integrate fermented foods: Kefir, kombucha, kimchi, kimchi, sauerkraut, yogurt, skyr, sourdough bread.
- Start once or twice a week if it's not already a habit.
- Test to see what's right for your gut.
- Ensure an adequate intake of fiber and omega-3:
- Fibers nourish good bacteria.
- Omega-3 supports the intestinal mucosa and bacterial performance: a dedicated episode in this program will help you choose them well.
- Taking care of your oral health:
- Avoid cavities, gingivitis and periodontitis
- The oral microbiota directly influences the intestinal microbiota, and bacteria from the mouth can be found even in endometriotic lesions.
- Schedule a dental check-up if it has not been done for a long time.
- Reduce what disrupts the microbiota:
- Alcohol, tobacco, chronic stress and some repeated medications are among the main factors that unbalance this ecosystem.
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